In two American Society for Cell Biology (ASCB) award essays published in the society’s journal Molecular Biology of the Cell, Mina Bissell, distinguished scientist in the Biological Systems & Engineering Division, and Eva Nogales, faculty structural biologist in the Molecular Biologist in the Molecular Biophysics & Integrated Bioimaging Division, each candidly describe their inspiring, personal journeys.
Several Biosciences Area personnel have been named as recipients of 2016 Berkeley Lab Director’s Awards. Yan Liang (Biological Systems & Engineering), Eva Nogales, and William Jagust (Molecular Biophysics & Integrated Bioimaging, MBIB) were honored with individual awards in Early Career, Scientific Achievement, and Societal Impact, respectively. Jill Fuss and Steven Yannone (MBIB) were the recipients of a team award in Technology Transfer for the launch of their company CinderBio. Jim Bristow (Biosciences Area Office, Trent Northen (Environmental Genomics & Systems Biology & Joint Genome Institute, JGI), and Susannah Tringe (JGI), along with Eoin Brodie and Peter Nico of the Earth and Environmental Sciences Area, were named in a team award in Service.
Eva Nogales, a faculty structural biologist in the Molecular Biophysics & Integrated Bioimaging Division, has been named 2016 Porter Lecturer by the American Society for Cell Biology (ASCB). The lecture is named in memory of Keith R. Porter, a pioneer in the use of electron microscopy in biology and one of the founders of ASCB, and is bestowed upon an eminent cell biologist each year at the ASCB Annual Meeting. Nogales will present the lecture on December 4 at ASCB 2016 in San Francisco, which will focus on the latest discoveries in the field, including CRISPR, and on building links from fundamental research to clinical issues.
In celebration of Nogales and Mina Bissell, a distinguished scientist in the Biological Systems & Engineering Division and awardee of the society’s 2016 E.B. Wilson Medal, the ASCB will host a dinner at the annual meeting in honor of these two accomplished Biosciences researchers.
Eva Nogales’ life and research work was highlighted in the PNAS Profile of August 12. The profile, written in recognition of her election to the National Academy of Sciences in 2015, accompanied the PNAS Inaugural Article of Nogales, a faculty structural biologist in the Molecular Biophysics & Integrated Bioimaging Division. In this article, titled “Near-atomic cryo-EM structure of PRC1 bound to the microtubule,” she uses cryo-EM to visualize, at a near-atomic level, how an essential component of the mitotic spindle maintains critical contact with microtubules to aid cell division.
The work of Eva Nogales and Jennifer Doudna, Molecular Biophysics & Integrated Bioimaging Division faculty scientists, were highlighted in the August 18 Nature technology feature article, “Let the structural symphony begin,” a discussion of the current “golden time to do hybrid methodologies,” according to Nogales. Structural biologists, such as Nogales who was interviewed for this article, now have “the tools to tackle important questions about cells’ molecular machinery that would have been impossible to answer just a few years ago.” Combining these imaging methods – selecting from an impressive suite of different imaging techniques – is an increasingly popular approach in the field of structural biology, in which X-ray crystallography has been the premier method for more than a century. According to the article, while “the most powerful insights come from (these) hybrid methodologies that integrate images from several different tools, ” it also has its drawbacks. Read the full article here.