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JGI Adds Actinobacteria Chapter in the Genomic Encyclopedia of Bacteria and Archaea

November 11, 2022

Open book with circular representations of microbial genomes above, all against a green background

In Cell Genomics, an international consortium led by researchers at the Joint Genome Institute team generated 824 new Actinobacteria genomes, which were were combined with nearly 5,000 publicly available ones and 1,100 metagenome-assembled genomes (MAGs) reconstructed from sequenced environmental samples in a previous study.

JGI Helps Develop Computational Pipeline for RNA Virus Sequences

October 3, 2022

close up of a needle in a haystack. (judyanded via Flickr CC BY NC 2.0)

In the journal Cell, scientists from a team led by researchers at Tel Aviv University in Israel, the National Center for Biotechnology Information, and the DOE Joint Genome Institute (JGI) describe a computational pipeline that can specifically scan for RNA virus sequences.

Biosciences Researchers Part of Genomic Analysis of Giant Bacteria Found in Guadeloupe Mangroves

June 23, 2022

Jean-Marie Volland at Donner lab.

In Science, a team led by Jean-Marie Volland, a scientist with joint appointments at the DOE Joint Genome Institute (JGI) and the Laboratory for Research in Complex Systems, and Silvina Gonzalez-Rizzo and Olivier Gros of the Université des Antilles, described the morphological and genomic features of a giant filamentous bacterium, along with its life cycle.

Two from Biosciences Elected American Academy of Microbiology Fellows

February 19, 2021

Two Biosciences Area researchers—Natalia Ivanova and Susannah Tringe—are among 65 new Fellows elected into the American Academy of Microbiology’s 2021 class. An honorific leadership group within the American Society for Microbiology, the mission of the Academy is to provide microbiological expertise in the service of science and the public. Fellows are elected annually through a highly-selective peer-review process based on their records of scientific achievement and contributions in the field of microbiology.

JGI Overhauls Perception of Inovirus Diversity

July 22, 2019

EM image of Pseudomonas phage Pf, an inovirus infecting Pseudomonas hosts. Inovirus capsids are long flexible filaments visible here after sample concentration and precipitation. (Courtesy of J. Driver and P. Secor, University of Montana)

Inoviruses are filamentous viruses with small, single-stranded DNA genomes and a unique chronic infection cycle. In Nature Microbiology, a team led by DOE Joint Genome Institute (JGI) researchers applied machine learning to publicly available microbial genomes and metagenomes to search for inoviruses. The search tool combed through more than 70,000 microbial and metagenome datasets, ultimately identifying more than 10,000 inovirus-like sequences compared to the 56 previously known inovirus genomes. The results revealed inoviruses are in every major microbial habitat—including soil, water, and humans—around the world.

“We’re not sure why we systematically manage to miss them; maybe it’s due to the way we currently isolate and extract viruses,” said the study’s lead author Simon Roux, a JGI research scientist in the Environmental Genomics group. Click here to read the full story on the JGI site.

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