In Cell Genomics, an international consortium led by researchers at the Joint Genome Institute team generated 824 new Actinobacteria genomes, which were were combined with nearly 5,000 publicly available ones and 1,100 metagenome-assembled genomes (MAGs) reconstructed from sequenced environmental samples in a previous study. The team also analyzed over 80,000 biosynthetic gene clusters (BGCs) for synthesis of secondary metabolites, in line with the JGI’s strategic initiatives. The work builds off more than a decade of work developing the Genomic Encyclopedia of Bacteria and Archaea (GEBA) compendium. Learn more on the JGI website.
Other JGI and Biosciences authors on the paper are Simon Roux, Dongying Wu, Sora Yu, Dan Udwary, Lee Call, Stephen Nayfach, Neha J. Varghese, Cody Webb, Krishnaveni Palaniappan, Jonathon Bertsch, Supratim Mukherjee, T.B.K. Reddy, Patrick P. Hajek, Marcel Huntemann, I-Min A. Chen, Alex Spunde, Alicia Clum, Nicole Shapiro, Zong-Yen Wu, Zhiying Zhao, Emiley A. Eloe-Fadrosh, Nigel J. Mouncey, Yasuo Yoshikuni, Tanja Woyke, and Nikos C. Kyrpides.