Manfred Auer, Staff Scientist and Director of Physical Analysis at the Joint BioEnergy Institute, has agreed to serve as the Head of Cellular and Tissue Imaging Department in the Molecular Biophysics & Integrated Bioimaging Division. Auer has been with Berkeley Lab since 2004, studying inner ear molecular machines, molecular mechanisms in cancer malignancy, biofilms, and bioenergy, as well as developing new imaging methods. He will succeed Bill Moses, who retired on June 29, after 36 years at Berkeley Lab. Moses’ research focused on advanced instrumentation for nuclear medical imaging, including Positron Emission Tomography (PET), which he also applied to the area of environmental bioremediation.
Downing Recognized with MSA Distinguished Scientist Award
Ken Downing, biophysicist senior scientist in the Molecular Biophysics & Integrated Bioimaging Division, has been honored as the recipient of the 2016 MSA Distinguished Scientist Award in the Biological Sciences. With the Distinguished Scientist Awards, the Microscopy Society of America (MSA) annually recognizes a preeminent senior scientist from each of the Biological and Physical Sciences who has a long-standing record of achievement during his or her career in the field of microscopy or microanalysis. Downing will be presented with the award at the Plenary Session of the Microscopy & Microanalysis 2016 Meeting on July 26, in Columbus, Ohio.
In 2010, Downing was elected MSA Fellow and recognized as a senior distinguished member of the society who has made significant contributions to the advancement of the field of microscopy through a combination of scientific achievement and service to the scientific community and the society itself.
Doudna Wins Tang Prize in Biopharmaceutical Science
Jennifer Doudna, faculty scientist in the Molecular Biophysics & Integrated Bioimaging Division, will share the prize with Emmanuelle Charpentier and Feng Zhang. They were honored “for the development of CRISPR/Cas9 as a breakthrough genome editing platform that promises to revolutionize biomedical research and disease treatment.” The awards, announced over the weekend in Taipei by Nobel laureate Y. T. Lee, each come with a cash prize of $1.24 million, in addition to funds for research. Read more at Berkeley NewsCenter.
Understanding the Key to Henipavirus Infection
In 1994, a virus emerged in Hendra, Australia, causing respiratory and neurological diseases. It was transmissible from horses to humans, with a mortality rate of 57% in humans and 89% in horses. Since then 2 additional deadly species have emerged in Malaysia and Africa, with evidence of 19 more. The members of this Paramyxoviridae family infect host cells through the fusion protein, F, which is embedded in the viral particle membrane. The bulk of the F protein, the ectodomain, protrudes from the membrane’s surface and undergoes a dramatic refolding to merge the virus and host membranes. At the Advanced Light Source (ALS) Beamline 8.2.2 in the Berkeley Center for Structural Biology, researchers used macromolecular crystallography to study the structure of the Hendra F protein ectodomain in its prefusion form and gain insight into its function. Read the ALS Science Brief.
Berkeley Lab Marks LGBT Pride Month
Lesbian, Gay, Bisexual, and Transgender Pride Month is celebrated each year in the month of June to honor the 1969 Stonewall riots in Manhattan. The Stonewall riots were a tipping point for the Gay Liberation Movement in the United States. As part of Pride Month, Berkeley Lab profiled scientists in the Biosciences and Computing Sciences Areas. One of the three to share their stories is Andrew Hagen, a postdoc in Cheryl Kerfeld’s group in the Molecular Biophysics & Integrated Bioimaging Division who was also a former graduate student with Jay Keasling at the Joint BioEnergy Institute. Read his about his experiences, along with those of Deb Agarwal and Elijah Goodfriend, on the Berkeley Lab Diversity & Inclusion website.
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