The Biosciences Strategic Plan (BSP) describes the vision for a national future strengthened by biological research achievements, and provides guidance for biosciences research activities at Berkeley Lab. Biosciences actively managed the BSP by continually evaluating its state and undertaking periodic refreshes to improve it. The plan was updated in 2019 to integrate computing approaches more thoroughly through the science strategies, structure the Health section to represent true enduring capabilities in Biosciences, and to more clearly articulate our aspirations in biodefense and biosecurity.

In 2018, Biosciences released a 5-year Progress Report that record progress towards meeting the 5-year milestones outlined in the 2016 version of the BSP. Success was measured by factors including publications, active funding for research, and establishment of new research programs. The report includes outlooks for future progress toward 10-year metrics, as well as an analysis of strengths and gaps of the associated research programs. These assessments helped Biosciences identify new program development opportunities and future strategic directions for the Area.

In 2023, Biosciences released a 10-year Summary Report that measured progress towards meeting the 10-year metrics outlined in the 2019 version of the BSP. Through the dedication of the entire Biosciences staff, the Area completed 66% of our 10-year metrics. Completed goal topics were researched and results had been made publically available through a publication, report, or patent. Of the remaining goals, progress has been made on 28%, with most in active research. Only 6% were deprioritized.