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Adam P. Arkin

Senior Faculty Scientist

Environmental Genomics and Systems Biology

  • Molecular EcoSystems Biology

Building: 955, Room 512C
Mail Stop: 955-512L
Phone: (510) 495-2116
Fax: (510) 486-6219
aparkin@lbl.gov
http://arkinlab.bio

Research Interests

Complex webs of life integrate and drive processes that affect outcomes from the individual health of a human or plant to entire planetary mineral cycles. Our laboratory leverages quantitative measurements, precision genetics, and model-driven experimentation to predict, control, and design biological function in the context of these webs. We are especially interested in understanding and ameliorating the processes that are interlinked with the radical changes our planet is and will be experiencing as climate is forced, populations grow, and pressures are placed on the resources we use to survive. We are also interested in what it might take to establish ourselves on the next planet as humanity begins to consider long term crewed missions on the Moon and Mars. Building safe, sustainable biotechnologies for environmental stewardship, health, food, and materials based on well-informed systems-level bioengineering is our main goal.

We are also committed to open, transparent, reusable and collaboratory model-driven science as exemplified through our work the the DOE Systems Biology Knowledgebase.

Selected Publications

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Dub-seq Used to Screen Phage Proteins for Antibiotic Properties

March 14, 2023

As conventional antibiotics continue to lose effectiveness against evolving pathogens, scientists are keen to employ the bacteria-killing techniques perfected by bacteriophages (phages), the viruses that infect bacteria. One major challenge is the difficulty of studying individual phage proteins and determining precisely how the virus wields these tools to kill their host bacteria. A team of researchers from Berkeley Lab, UC Berkeley, and Texas A&M University worked together on a high-throughput genetic screen to identify which part of the bacteria the phages were targeting.

Ten Simple Rules for Getting and Giving Credit for Data

November 1, 2022

Generating and analyzing data associated with scientific research can be challenging and complicated, to say the least. But the importance of sharing and giving credit to those who produced the data is foundational to furthering the impact of the work. Learn more about ten simple rules for getting and giving credit for data. 

Small-scale Changes in Environment Can Have Large Effects on Microbial Communities

May 12, 2022

A Berkeley Lab team analyzed the genotypes and phenotypes of several Arthrobacter strains to correlate cellular functions to their location at varying depths within a single sediment core and in nearby groundwater. They found that Arthrobacter, as a genus, has remarkable flexibility in altering its suites of carbon degradation genes. This genomic variation was found to be linked to the individual strain’s environment and is the basis for Arthrobacter’s ability to break down a wide variety of complex carbon sources. 

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