On April 29, 2021, Berkeley Lab hosted a second workshop to identify the most pressing barriers to wider adoption of single-cell sequencing and omics technologies, and to discuss solutions to remedy those barriers in order to drive discovery. The workshop report is now available for download.
One of the tools that researchers can apply to study the transcription factors that control how genes are turned on is known as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan O’Malley, who leads the JGI Sequencing Technologies Group. In a Nature Methods article, JGI researchers led by co-first authors Leo Baumgart and Juna Lee developed two approaches that build upon the DAP-seq technology O’Malley developed. Read more here on the JGI website.
On January 23, 2020, Berkeley Lab hosted a workshop on opportunities afforded by single-cell technologies for energy and environmental science, as well as conceptual and technological grand challenges that must be tackled to apply these powerful approaches to plants, fungi and algae. This event, which was spearheaded by Diane Dickel in the Environmental Genomics and Systems Biology Division, brought together a diverse group of leaders in functional genomics technologies from academia, the National Laboratories, and local research institutions.