Researchers led by Berkeley Lab Biosciences’ Cheryl Kerfeld (MBIB), who holds a joint appointment at the MSU-DOE Plant Research Laboratory, have provided the first atomic-level resolution picture of an intact bacterial microcompartment (BMC) shell.
The intact shell and component proteins from the saltwater bacterium Haliangium ochraceum were crystallized at Berkeley Lab; X-ray diffraction data were collected at the Lab’s Advanced Light Source (ALS) and at the Stanford Synchrotron Radiation Lightsource.
Details of the BMC shell’s structure and composition were published in the journal Science.
“Having the full structural view of the bacterial organelle membrane can help provide important information in fighting pathogens or bioengineering bacterial organelles for beneficial purposes,” said Kerfeld. Read more in the News Center release.