The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made. In a paper appearing in the journal PLOS Biology, described the work of researchers at the University of California, Berkeley, and Pfizer Worldwide Research and Development. Faculty scientist Jamie Cate, Structural Biology Department Head in the Molecular Biophysics and Integrated Bioimaging Division, was a senior author of this study. Read the full story in Berkeley News.
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