An international team of researchers that included developers of the Phenix software suite performed an analysis of AlphaFold predictions, comparing them with both high-quality experimental data and experimentally determined structures. Their results led them to conclude that AI-based protein structure predictions are best considered to be exceptionally useful hypotheses, and that experimental measurements remain essential for confirmation of the details of protein structures.
Nigel Moriarty, Wave Wizard
Experimentation abounds for computational research scientist Nigel Moriarty. A lifelong stamp collector and surfer, Moriarty approaches culturally-distinct pockets of society with the curiosity of an anthropologist. And applying quantum chemistry and theoretical physics to drug design is part of his day-to-day work writing software with MBIB’s PHENIX group.
Biosciences Area FY24 LDRD Projects
The projects of 21 Biosciences Area scientists and engineers received funding through the FY24 Laboratory Directed Research and Development (LDRD) program.
Hura, Tsutakawa named Science Deputy, Structural Biology Department Head
Molecular Biophysics and Integrated Bioimaging (MBIB) Division Director Junko Yano has announced that staff scientists Greg Hura and Susan Tsutakawa have officially assumed the roles of MBIB Science Deputy and Head of the Structural Biology Department, respectively. They have been serving in these positions on an interim basis since August 2021.
How Algae Use Memory to Adapt to Sudden Changes in Sunlight
A new study co-led by Graham Fleming, a senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, and Krishna Niyogi, a faculty scientist in MBIB, reveals the precise molecular machinery that underpins photoprotective memory in green algae. The results may help scientists develop more productive plants and improve crop yields.
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