Biosciences researchers have used Collaborative Cross mice, a mouse model system designed to mimic the diversity of human populations, to identify a set of genetic factors that could help refine treatment approaches for a fast-growing form of breast cancer.
Structural Biology Brings Chemotherapy Resistance Into High Resolution
Biosciences researchers conducted the first ever structural analysis of a key protein involved in DNA damage repair and cancer. While the narrative around cancer chemotherapy has historically focused on DNA damage repair pathways, findings from this study underscore the role of RNA-mediated processes on chemotherapy response, which could have major implications for cancer treatment outcomes.
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