Microbiome Signature Could Predict Post-op Enterocolitis in Hirschsprung Disease Patients
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Biosciences Area researchers, in collaboration with colleagues at Nanjing Medical University in China, performed the first study to prospectively investigate the gut microbiome in relation to Hirschsprung-associated enterocolitis (HAEC), a leading cause of death in Hirschsprung disease patients. They identified a microbiome signature that might predict the development of postoperative HAEC. In addition, they found that exclusive breastfeeding might reduce the risk of HAEC through modulation of the intestinal microbiome.
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