An international team of researchers that included developers of the Phenix software suite performed an analysis of AlphaFold predictions, comparing them with both high-quality experimental data and experimentally determined structures. Their results led them to conclude that AI-based protein structure predictions are best considered to be exceptionally useful hypotheses, and that experimental measurements remain essential for confirmation of the details of protein structures.
Researchers Capture Elusive Missing Step in Photosynthesis
After decades of effort, scientists have revealed atomic-scale details of the water splitting step of photosynthesis, the chemical process that generates the air we breathe. The latest work adds to our understanding of photosynthesis and will aid the development of fully renewable alternative energy sources.
Adams Appointed ALD for Biosciences
Berkeley Lab Director Mike Witherell has appointed Paul Adams to the position of Associate Lab Director (ALD) for Biosciences. Adams has been serving as the interim ALD for the Biosciences Area since 2021, taking over for Mary Maxon, who is now with Schmidt Futures. Over the past two decades, Adams has played an important role promoting Berkeley Lab’s leadership in structural biology nationally and internationally. As ALD, Adams will continue to advance the Area’s scientific vision and operations excellence while advancing IDEA principles and broadening outreach to institutions serving groups that are underrepresented in STEM.
Adams and Keasling Receive DOE Secretary’s Honor Award
In a virtual ceremony on January 24, Associate Laboratory Director for Biosciences Paul Adams and Jay Keasling, Biological Systems and Engineering senior faculty scientist, were among several Lab staff who received the Department of Energy’s (DOE) highest form of employee recognition for excellence and achievements.
Small-scale Changes in Environment Can Have Large Effects on Microbial Communities
A Berkeley Lab team analyzed the genotypes and phenotypes of several Arthrobacter strains to correlate cellular functions to their location at varying depths within a single sediment core and in nearby groundwater. They found that Arthrobacter, as a genus, has remarkable flexibility in altering its suites of carbon degradation genes. This genomic variation was found to be linked to the individual strain’s environment and is the basis for Arthrobacter’s ability to break down a wide variety of complex carbon sources.
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