Though once thought to be “junk DNA,” enhancers are extremely important, regulating the expression of specific genes that ultimately determine a cell’s properties and functions. However, there are many more enhancers than genes and their relationship is unclear. A team of scientists in the Environmental Genomics & Systems Biology Division have turned their attention to this relationship and the overall importance of enhancers to development. By better linking the genomic complement of an organism with its expressed characteristics, their work offers new insights that further the growing field of systems biology, which seeks to gain a predictive understanding of living systems.
Silencing Is Golden: Scientists Image Molecules Vital for Gene Regulation
In two new studies, a team of researchers led by Eva Nogales, senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, has gained insight into the structure and function of molecules that act at the genetic level to give rise to different types of cells.
JGI Helps Track Microbial Diversity Through the Terrestrial Subsurface
In collaboration with a team led by longtime collaborator Jill Banfield of the University of California, Berkeley and Cathy Ryan of the University of Calgary in Canada, JGI researchers investigated samples collected at Utah’s Crystal Geyser over one of its complex, five-day eruption cycles. Genome-resolved metagenomics, single-cell genomics, and geochemical analyses were integrated to show that samples taken during each phase contain microbial communities that are distinctive in terms of both composition and metabolic function. The report was published January 29, 2018 in Nature Microbiology. Read the full story on the JGI website.
Diversity Senior Leadership Council Launched at the Lab
Berkeley Lab Director Witherell, in partnership with the Diversity, Equity, and Inclusion (DEI) Office, has announced the launch of Berkeley Lab’s DEI Senior Leadership Council (SLC). Members of the council include Biosciences Associate Laboratory Director Mary Maxon and Biological Systems & Engineering Division Director Blake Simmons. They, along with ten other councilmembers, will provide senior leadership with support and guidance toward achieving the Lab’s strategic DEI goals.
In his announcement, Witherell said that the SLC “will help carry out our commitment to ensure that diversity, equity, and inclusion become hallmarks of the Berkeley Lab culture. This council will provide senior management’s support and guidance toward achieving the Lab’s strategic DEI goals. The leadership and perspectives of our council members will be invaluable as we move forward with our strategy and vision for our organization.” Go to the DEI website to learn more.
TEDx Talk by BSE’s Director Blake Simmons Now Available
Blake Simmons, Director of the Biological Systems and Engineering Division, gave a talk at TEDxSonomaCounty on November 4, 2017 entitled “A World Without Limits through Biomanufacturing of Carbon”. The video of the talk is now available.
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