The projects of 22 Biosciences Area scientists and engineers received funding through the FY23 Laboratory Directed Research and Development (LDRD) program.
How to Edit the Genes of Nature’s Master Manipulators
A team led by CRISPR pioneer Jennifer Doudna and her longtime collaborator Jill Banfield has developed a clever tool to edit the genomes of bacteria-infecting viruses called bacteriophages using a rare form of CRISPR. The ability to easily engineer custom-designed phages—which has long eluded the research community—could help researchers control microbiomes without antibiotics or harsh chemicals, and treat dangerous drug-resistant infections. A paper describing the work was recently published in Nature Microbiology.
Congratulations to Biosciences Area Director’s Award Recipients
Each year, the Berkeley Lab Director’s Achievement Award program recognizes outstanding contributions by employees to all facets of Lab activities. Several Biosciences Area personnel are among the 2022 honorees.
Structures Signal Fresh Targets for Anticancer Drugs
Genentech researchers used a suite of methods, including small-angle X-ray scattering (SAXS) at the Advanced Light Source (ALS) to learn how an assembly of three proteins works together to transmit signals for cell division. The work reveals new targets for the development of drugs that fight certain types of cancer, including lung, colorectal, and pancreatic.
Bioscientists to Receive DOE Funding for Biomanufacturing and Microbiome Research
Biosciences researchers are among the recipients of four new DOE awards. Two awards will focus on reducing carbon emissions while producing bioenergy. The other two are aimed at understanding the role of microbiomes in the biogeochemical cycling of elements like carbon.
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