A research team led by Nitash Balsara, a senior faculty scientist in the Materials Sciences Division (MSD) at Berkeley Lab and professor of chemical and biomolecular engineering at UC Berkeley, has adapted a powerful electron-based imaging technique to obtain an image of atomic-scale structure in a synthetic polymer. The team of researchers from Berkeley Lab and UC Berkeley included the late Ken Downing of the Molecular Biophysics & Integrated Bioimaging Division.
Scientists Capture Photosynthesis in Unprecedented Detail
Using the SLAC National Accelerator Laboratory’s Linac Coherent Light Source (LCLS) X-ray laser, an international collaboration led by scientists at Berkeley Lab and SLAC captured the all four stable oxidation states of photosystem II— plus two transitional states—at natural temperature and the highest resolution to date.
Biomaterials Workshop Report Released
On July 16-17, 2018, Berkeley Lab hosted a workshop on opportunities to develop new materials made by biology that focused on inorganic and organic/inorganic composites. This event brought together researchers from across the lab to identify areas for collaborative research that bridge biology, chemistry, materials science, and computing. The workshop was held in anticipation of two recent workshops, one each hosted by the Department of Energy and Department of Defense, to develop a Berkeley Lab perspective for these types of materials. Caroline Ajo-Franklin, Peter Fischer, and Jay Keasling hosted the two-day meeting. The workshop report, which was compiled based on participant discussions and was reviewed by the participants, is now available for download.
Recent Highlights from the Berkeley Center for Structural Biology Beamlines
Data collected at the Berkeley Center for Structural Biology (BCSB) in the Advanced Light Source (ALS) has provided new structural insights into an antibody that protects against the bacterium that causes meningitis and sepis; a protein that unwinds quadruple DNA/RNA helixes; and an antibody targeting interleukin-2 that may provide a means of treating autoimmune disorders.
Photosynthesis, Like a Moss
Using cryo-electron microscopy (cryo-EM), which allows an unprecedented level of resolution, Biosciences researchers compared the structure of photosystem I in the moss Physcomitrella patens with its structure in the small flowering land plant Arabidopsis thaliana, and in the green alga Chlamydomonas reinhardtii. Because moss evolved after algae but before vascular land plants, such comparisons can shed light on how plants evolved to move from the ocean to land.
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