The projects of eleven Biosciences Area scientists and engineers received funding through the FY2016 Laboratory Directed Research and Development (LDRD) program. These projects cover a broad range of topics, including energy science technology applications, novel computing technologies, and mechanistic understanding of multi-scale interactions among molecules, microbes, plants, metazoans, the abiotic environment, and their feedbacks. Together, these efforts account for nearly 14% of the $25.3 million allocated. Lab-wide, 84 proposals were selected from a field of 179.