Found in microbial communities around the world, Aspergillus fungi are pathogens, decomposers, and important sources of biotechnologically-important enzymes. In a study published ahead the week of January 8, 2018 in the Proceedings of the National Academy of Sciences, a team led by researchers at the Technical University of Denmark (DTU), the Joint Genome Institute (JGI), and the DOE’s Joint BioEnergy Institute (JBEI) report the first results of a long-term plan to sequence, annotate and analyze the genomes of 300 Aspergillus fungi. These findings are a proof of concept of novel methods to functionally annotate genomes in order to more quickly identify genes of interest. Read more on the JGI website.
JBEI and JGI Partner with LanzaTech in New DOE Technology Commercialization Fund Grant
LanzaTech is looking into new routes to capture carbon capture and biomanufacture new products. In order to accelerate development while at the same time reducing costs and increasing throughput, LanzaTech is partnering with Department of Energy (DOE) laboratories: Berkeley Lab (LBNL); DOE Joint Genome Institute (DOE JGI); Sandia National Laboratories (SNL); the Joint BioEnergy Institute (JBEI), and Oak Ridge National Lab to develop new foundational technologies that will open new frontiers in this space. Under a Technology Commercialization Fund (TCF) grant by the DOE, LanzaTech, with LBNL, SNL and JBEI will focus on microfluidics, as a way to shrink the physical footprint of LanzaTech’s manufacturing facility, and reducing the cost and time needed to test the outcome of each experiment. DOE JGI will synthesize 1 million base pairs of DNA for novel pathways and to construct a library for modification of every gene in LanzaTech’s organism. Read the press release.
To Find New Biofuel Enzymes, It Can Take a Microbial Village
A new study led by researchers at the Department of Energy’s Joint BioEnergy Institute (JBEI), based at Lawrence Berkeley National Laboratory (Berkeley Lab), demonstrates the importance of microbial communities as a source of stable enzymes that could be used to convert plants to biofuels. The study, recently published in the journal Nature Microbiology, reports on the discovery of new types of cellulases, enzymes that help break down plants into ingredients that can be used to make biofuels and bioproducts. The cellulases were cultured from a microbiome. Using a microbial community veers from the approach typically taken of using isolated organisms to obtain enzymes. Read more in the Berkeley Lab’s News Center.
Genome Research Challenges Previous Understanding of the Origin of Photosynthesis
Plant biologists at Lawrence Berkeley National Laboratory (Berkeley Lab), in collaboration with colleagues from the California Institute of Technology (Caltech), have reconstructed the evolutionary history of photosynthesis to provide new insight into the yet-unfolding story of its origins.
JBEI Researchers Improve Membrane Protein Expression And Function Using Genomic Edits
Development of robust microbial platforms for bioproduction requires strains that have been engineered to have efficient carbon uptake, energy generation, tolerance to biomass pretreatment byproducts and the export of final product. Many of these optimizations require expression and overexpression of native and heterologous membrane proteins. Over the years, scientists at the U.S. Department of Energy’s Joint BioEnergy Institute (JBEI), and others have successfully found many such engineering targets. However, JBEI has also found that expression of membrane proteins is challenging and can also impact the microbial growth, thus negatively limiting the use of these discoveries. Read more from JBEI.
- « Previous Page
- 1
- …
- 22
- 23
- 24
- 25
- 26
- …
- 37
- Next Page »
Was this page useful?
Send
