Amy Herr, faculty scientist in Biological Systems and Engineering, was among 175 inductees announced by the Academy on December 13. Election is a “distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society.” Herr is renowned for innovative engineering analysis of complex biological systems, with an emphasis on analytical tools and diagnostics. Read more at BerkeleyNews.
Social Media Feature Highlights 7 Lab Imaging Tools Pushing Science Forward
Lab scientists are developing new ways to see the unseen. Seven imaging advances, including two from the Biosciences Area, are helping to push science forward, from developing better batteries to peering inside cells to exploring the nature of the universe. The animation on the left shows a 3-D journey inside the center of cells, recently described in Cell Reports by scientists in the National Center for X-ray Tomography at the Advanced Light Source. These techniques were previously reported in the Berkeley Lab News Center and have been compiled into this listicle.
Finding Diamonds in the Rough
New crystallography finding by JBEI and GLBRC benefits bioenergy industry
During the kraft process used to convert wood into wood pulp, the structural material lignin is partially converted into molecules like stilbene. Stilbenes are also naturally occurring in plants and some bacteria, and may play a role in plant pathogen resistance.
Currently, the deconstruction of plant biomass into cellulose and lignin is an expensive process. Lignin accounts for about 30 percent of plant cell wall carbon, and its conversion into chemicals or fuels could have a significant positive impact on the economics of processing lignocellulosic biomass. Enzymes capable of producing useful compounds from the breakdown of stilbenes and similar molecules could be employed for this. Collaborators from two of the Department of Energy Bioenergy Research Centers now have gained first-hand insight into how a stilbene cleaving oxygenase (SCO) carries out this unusual chemical reaction.
Genes, Early Environment Sculpt the Gut Microbiome
Researchers from Berkeley Lab’s Biological Systems & Engineering (BSE) Division and the Department of Energy’s Pacific Northwest National Laboratory found that genes and early environment play big roles in shaping the gut microbiome. The microbes retained a clear “signature” formed where the mice were first raised, and the characteristics carried over to the next generation. The findings, published on November 28 in the journal Nature Microbiology, could potentially be used to develop designer diets optimized to an individual’s microbiome.
The BSE research team included first author Antoine Snijders, corresponding author Jian-Hua Mao, and Sasha Langley. Read more on the Berkeley Lab News Center.
Brain Initiatives Generate Tsunami of Neuroscience Data
Around the world, various ‘Brain Initiatives’ are generating a tsunami of neuroscience data. But without a coherent strategy to analyze, manage and understand the data, advancements in the field will be limited. That’s why Kristofer Bouchard, research scientist in Biological Systems & Engineering Division, assembled an international team of interdisciplinary researchers to develop a plan to overcome the big data challenge. Read more at the Computational Research Division News Page.
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