Simon Roux

Biologist Staff Scientist

DOE Joint Genome Institute

Secondary Affiliation: Environmental Genomics and Systems Biology

Molecular EcoSystems Biology

sroux@lbl.gov
https://jgi.doe.gov/our-science/scientists-jgi/environmental-genomics/
https://simroux.github.io

Programs & Initiatives

JGI Viral Genomics Group
JGI Metagenome Program

Research Interests

Viruses of microbes
Virus discovery
Virus-host interactions
Comparative Metagenomics

Selected Publications

LinkedIn Profile
ResearchGate Profile

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The JGI Doubles Down on Known Protein Families

October 16, 2023

Through a novel approach detailed in Nature, a massive computational analysis of microbiome datasets by the JGI focuses on unveiling protein functional diversity.

A Tool to Find Nomadic Genes that Help Microbes Adapt

September 21, 2023

Mobile genetic elements (MGEs) are genetic entities that seek to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool recently described in Nature Biotechnology called geNomad identifies and classifies MGEs based upon their gene content and their genetic sequences. The software was created by researchers under the direction of JGI Microbiome Data Science Group Lead Nikos Kyrpides.

JGI Creates a New Matchmaker for Phages and their Hosts

June 7, 2023

To do anything, viruses must find a host, and not just any host will do. It must be a specific host the virus has adapted to commandeer. For bacteriophage viruses, these hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of ecosystems. However, matching these viral genetic sequences to their hosts is crucial to understanding what these viruses can do. Building on existing virus-host prediction approaches, researchers have created a new program called iPHoP (pronounced “eye-pop”, freely available online).

Research Interests

About Biosciences

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