Derek Mendez

Project Scientist

Molecular Biophysics and Integrated Bioimaging

Structural Biology

dermen@lbl.gov
https://stackoverflow.com/users/2077270/dermen

Curriculum Vitae

Research Interests

leadership class computing (NERSC, OLFC)

X-ray free electron lasers

protein crystallography

time-resolved protein solution scattering

fluctuation X-ray scattering

Selected Publications

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Crystallography for the Misfit Crystals

January 19, 2022

Nicholas Sauter, a computer senior scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, is co-leading a team working to provide a better way for scientists to study the structures of the many materials that don’t form tidy single crystals. Their new technique, called small-molecule serial femtosecond X-ray crystallography, or smSFX, supercharges traditional crystallography with the addition of custom-built image processing algorithms and an X-ray free electron laser (XFEL). In a paper published in Nature, the team demonstrated proof-of-principle for smSFX and reported the previously unknown structures of two metal-organic materials known as chacogenolates.

Chloro-phylling in the Answers to Big Questions

December 1, 2021

A team of scientists, including many in the Molecular Biophysics and Integrated Bioimaging Division, uncovered new details about the reaction that powers photosynthesis. Understanding this reaction could lead to world-changing advances in technology, medicine, or energy––and also gives insight into how the enzyme photosystem II produces the oxygen we breathe. Their latest work was recently published in Nature Communications and two of the authors, Vittal Yachandra and Philipp Simon, spoke with Strategic Communications about that, shooting stuff with lasers, and why they chose this field of research.

Research Interests

About Biosciences

Divisions & User Facility

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