Aparajitha Srinivasan placed third and Ying Wang was awarded People’s Choice in the Berkeley Lab Research SLAM competition on September 22. Srinivasan, a postdoctoral researcher at the Joint BioEnergy Institute (JBEI) in the Biological Systems and Engineering (BSE) Division, detailed her research on utilizing computational modeling to select the best routes to creating aroma additives. The Environmental Genomics and Systems Biology (EGSB) Division’s Wang covered how to determine which microbes eat which carbon molecules.
JGI Helps Develop Computational Pipeline for RNA Virus Sequences
In the journal Cell, scientists from a team led by researchers at Tel Aviv University in Israel, the National Center for Biotechnology Information, and the DOE Joint Genome Institute (JGI) describe a computational pipeline that can specifically scan for RNA virus sequences.
Bioscientists to Receive DOE Funding for Biomanufacturing and Microbiome Research
Biosciences researchers are among the recipients of four new DOE awards. Two awards will focus on reducing carbon emissions while producing bioenergy. The other two are aimed at understanding the role of microbiomes in the biogeochemical cycling of elements like carbon.
BCSB Confirms AI-predicted Structure of Key Rotavirus Site
The effects of a stomach flu can range from pesky to deadly. Researchers recently used an AI program to predict the structure of a common rotavirus and collaborated with a Biosciences researcher working at the Advanced Light Source to validate their novel finding.
Structural Imaging at ALS Yields New Insights into DNA Repair Enzyme
PARP1 is an enzyme that senses DNA damage and sends a cellular signal to carry out repair. It has been found to be upregulated in several carcinomas and inhibiting its activity has been shown to repress tumor growth and metastasis. PARP1 has also emerged as a promising therapeutic target for Alzheimer and Parkinson diseases, where attenuating the enzyme’s hyperactivity can help cells survive. To better understand the regions of PARP1 that various inhibitors attack, an international team of researchers captured the first snapshot of the enzyme in the active state it adopts after detecting DNA damage.
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