Researchers from the Joint BioEnergy Institute (JBEI) developed a new framework that reduces the time of developing novel bioproducts. This new workflow, called Product Substrate Pairing (PSP), has already shown great promise for engineering strains that can convert common bacterial food sources into target molecules.
A Tool to Find Nomadic Genes that Help Microbes Adapt
Mobile genetic elements (MGEs) are genetic entities that seek to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool recently described in Nature Biotechnology called geNomad identifies and classifies MGEs based upon their gene content and their genetic sequences. The software was created by researchers under the direction of JGI Microbiome Data Science Group Lead Nikos Kyrpides.
ABPDU Hosts Scale-Up Facilities Expo
The ABPDU’s Scale-Up Facilities Expo took place on Aug. 7, 2023, bringing together scale-up facilities and startup researchers. The all-day event saw 249 attendees from 29 countries attend 32 facility presentations, giving them the opportunity to learn about a variety of scale-up capabilities beyond those available at the ABPDU.
Biosciences Researchers Launching Biopreparedness Projects
Two scientists in the Area, Greg Hura and Vivek Mutalik, are heading up research projects that are part of the Department of Energy’s Biopreparedness Research Virtual Environment (BRaVE) initiative. Yasuo Yoshikuni, a scientist at the Joint Genome Institute, is part of a third project that is being led by Brookhaven National Laboratory. These projects will leverage bioimaging expertise to develop better therapies and vaccines for viruses, develop a high-throughput platform to rapidly design countermeasures to drug-resistant pathogens, and unlock the molecular basis of plant-pathogen interactions to create resilient bioenergy crops.
Agile BioFoundry Selects New Projects to Decarbonize Industries and Accelerate Innovation
The Agile BioFoundry (ABF), supported by the U.S. Department of Energy (DOE) Bioenergy Technologies Office (BETO), announced the selection of five external collaborations totaling over $3 million to conduct research and development needed to accelerate the U.S. biomanufacturing sector.
The awardees will collaborate with scientists from the ABF consortium, leveraging DOE national laboratory capabilities to address challenges in biomanufacturing.
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