A team of Molecular Biophysics and Integrated Bioimaging Division researchers used synchrotron technology unique to the Advanced Light Source (ALS) at Berkeley Lab to probe the conformational states behind electron bifurcation.
Watching the Enzymes that Convert Plant Fiber into Simple Sugars
Researchers in the Berkeley Synchrotron Infrared Structural Biology (BSISB) Imaging Program developed a technique that combines a novel microfluidic device and infrared spectroscopy to study how a cellulose-degrading enzyme works in real time.
Giant Bacteria Genome Yields Clues to How it Meets its Energy Needs
The Biosciences Area’s Nathalie Elisabeth and Jean-Marie Volland collaborated on a study led by researchers from Cornell that produced the first full genome of a species of giant bacteria. Members of the Epulopiscium genus, the largest known heterotrophic bacteria, are a million times larger than E. coli. They live in the guts of tropical marine fish, an environment rich in sodium, which the team’s analysis suggests the bacteria use, along with polysaccharides from their host’s diet, to meet their outsize energy requirements.
Rising Sea Levels Could Mean Higher Wetlands Methane Emissions
Area researchers led a team that examined the microbial, chemical, and geological features of 11 wetland zones in the Bay Area. Their findings indicate that the factors governing how much greenhouse gas is stored or emitted in natural landscapes are more complex and difficult to predict than previously thought.
Researchers Assess AlphaFold Model Accuracy
An international team of researchers that included developers of the Phenix software suite performed an analysis of AlphaFold predictions, comparing them with both high-quality experimental data and experimentally determined structures. Their results led them to conclude that AI-based protein structure predictions are best considered to be exceptionally useful hypotheses, and that experimental measurements remain essential for confirmation of the details of protein structures.
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