Vivek Mutalik
Staff Scientist
Building: Aquatic Park Station 717 Potter St #180B, 977-0180B, CA 94710, Room 180B
Mail Stop: 977-180B
VKMutalik@lbl.gov
Links
Divisions
Environmental Genomics and Systems Biology
- Comparative and Functional Genomics
Secondary Affiliation:
Biological Systems and Engineering
- BioEngineering & BioMedical Sciences
- Biodesign
Research Interests
- Developing high-throughput functional discovery platform for thousands of microbial genes, phage genes and extending it to metagenomic samples
- Discovery of bacteriophage-host interaction determinants, mechanistic insights into antibiotic resistance and phage resistance, and how they impact host fitness
- Approaches for doing esigned manipulation of microbial communities
- Engineering of phages, phage particles for diverse applications
- Rational design of phage cocktails with antibiotics for phage therapy applications
- Synthetic genetic parts for phylogenetically distinct and industrially important microbes and rules for their functional composition.
PRESS:
Cataloging Nature’s Hidden Arsenal: Viruses that Infect Bacteria
https://naturemicrobiologycommunity.nature.com/posts/a-tale-of-tailocins-bacterial-stabbing-tools
https://mammoth.bio/2020/10/28/mammoth-interviews-vivek-k-mutalik-phd-scientist-at-lbnl-and-co-founder-of-felix-biotechnology/
https://phage.directory/capsid/interview-vivek-mutalik
Programs & Initiatives
Recent Publications
Related News
Biosciences Researchers Launching Biopreparedness Projects
Two scientists in the Area, Greg Hura and Vivek Mutalik, are heading up research projects that are part of the Department of Energy's Biopreparedness Research Virtual Environment (BRaVE) initiative. Yasuo Yoshikuni, a scientist at the Joint Genome Institute, is part of a third project that is being led by Brookhaven National Laboratory. These projects will leverage bioimaging expertise to develop better therapies and vaccines for viruses, develop a high-throughput platform to rapidly design countermeasures to drug-resistant pathogens, and unlock the molecular basis of plant-pathogen interactions to create resilient bioenergy crops.
Dub-seq Used to Screen Phage Proteins for Antibiotic Properties
A team of researchers from Berkeley Lab, UC Berkeley, and Texas A&M University worked together on a high-throughput genetic screen to identify which part of the bacteria bacteriophage viruses were targeting.
