In a new study, faculty scientist Mohammad Mofrad from the Molecular Biophysics & Integrated Bioimaging Division, together with his Ph.D. student Mohammad Soheilypour, shed light on a complex system of cell regulation that acts as a form of quality control for the transport of genetic information out of the nucleus. Getting a more complete picture of how genetic information gets expressed in cells is important in disease research, the researchers say.

“Some components of this machinery are dysregulated in various types of cancers,” explains Mofrad. “Understanding the molecular mechanism of genetic information transport and quality control would substantially improve the current knowledge about various types of cancers and other human diseases.” Their findings were published in the journal Scientific Reports of November 2. Read the full story on the Berkeley Lab News Center.

Scientists have gained insight on how some molecules are allowed to enter and exit the nucleus while keeping other molecules out. Their research, led by Mohammad Mofrad in the Molecular Biophysics & Integrated Bioimaging Division, is a step forward in building a more comprehensive understanding of nuclear pore complex function, which has numerous implications in … Read more »