Researchers at the Scripps Institution of Oceanography in San Diego used the Berkeley Center for Structural Biology’s 8.2.2 beamline at the Advanced Light Source to identify structural details of an enzyme that produces a versatile anti-cancer molecule. By virtue of the its unique, ringed structure the molecule crosses the blood-brain barrier and could be instrumental in fighting difficult-to-access brain cancers.
Molecular Hijacking of a MicroRNA by the Hepatitis C Virus
Viruses have evolved a wide variety of ways to exploit parts of their host cells to avoid detection and to grow. Researchers at the Scripps Research Institute and the Berkeley Center for Structural Biology are learning more about how hepatitis C works to deceive its host cells.
Safely Studying Dangerous Infections Just Got A Lot Easier
A team of researchers led by NCXT Director Carolyn Larabell, in collaboration with scientists at Heidelberg University in Germany, used a technique called soft X-ray tomography (SXT) to quickly scan and analyze human lung cells infected with SARS-CoV-2. SXT not only significantly shortens the time frame, but provides more detail—increasing the chances of distinguishing subtle changes in the cell.
NIH Funds $40M Study to Compare Tau Tracers
The National Institutes of Health (NIH) recently awarded more than $40 million, distributed over five years, for a project that aims to compare two positron emission tomography (PET) imaging agents widely used to visualize misfolded tau protein—one of the hallmarks of Alzheimer disease (AD) and other dementias—in living brains. The effort will be led by co-principal investigators Suzanne Baker, a computational staff scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, and Tharick Pascoal, an assistant professor in the department of psychiatry at the University of Pittsburgh (Pitt).
Two from Biosciences Area Named AAAS Fellows
The American Association for the Advancement of Science (AAAS) has announced that 564 of its members—among them four scientists at Berkeley Lab—have been elected Fellows as part of the 2021 class. The two newly named Fellows from the Biosciences Area are: Eva Nogales, a senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, and Scott Baker an affiliate with the Joint BioEnergy Institute (JBEI).
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