Stanford researchers have used cryogenic 3D imaging at the National Center for X-ray Tomography (NCXT) to identify a new pathway for clearing misfolded proteins from cells. This work presents a potential therapy target for age-related disorders like Alzheimer, Parkinson, and Huntington Diseases.
Each year, the Berkeley Lab Director’s Achievement Award program recognizes outstanding contributions by employees to all facets of Lab activities. Several Biosciences Area personnel are among the 2022 honorees.
A team of researchers led by NCXT Director Carolyn Larabell, in collaboration with scientists at Heidelberg University in Germany, used a technique called soft X-ray tomography (SXT) to quickly scan and analyze human lung cells infected with SARS-CoV-2. SXT not only significantly shortens the time frame, but provides more detail—increasing the chances of distinguishing subtle changes in the cell.