Most organisms use oxygen to convert food into energy. However, in environments with little or no oxygen, life had found other ways to produce energy, using a process called fermentation. To better understand the range of bacteria and archaea that rely on this form of metabolism, researchers at UC Davis and UC Santa Barbara recently compiled a list of with more than 8,300 organisms from multiple sources, including the DOE Joint Genome Institute (JGI) and the DOE Systems Biology Knowledgebase (KBase). The researchers also built an interactive browser that allows other researchers to study the genomes and predict the metabolic abilities of microbes that are likely to thrive in environments with little or no oxygen.
The JGI Doubles Down on Known Protein Families
Through a novel approach detailed in Nature, a massive computational analysis of microbiome datasets by the JGI focuses on unveiling protein functional diversity.
The JGI’s Genomes OnLine Database Celebrates 25 Years of Data Contextualization
Since its launch 25 years ago, the Genomes OnLine Database has matured from six projects on a spreadsheet into a flagship genomic metadata repository, making curated microbiome metadata that follows community standards freely available, and enabling large-scale comparative genomics analysis initiatives.
JGI Leads Large-Scale Effort to Develop a Genomic Catalog of Earth’s Microbiomes
Microorganisms play key roles in regulating global nutrient cycles but only a small fraction has been identified and an even smaller number has been successfully cultured in a lab for study. In Nature Biotechnology, the known diversity of bacteria and archaea has now expanded by 44% through a publicly available collection of more than 52,000 microbial genomes from environmental samples. Of that number, 70% of the novel genome sequences were previously unknown, not yet cultured in the lab. The work results from a JGI-led collaboration involving more than 200 scientists around the world, KBase and NERSC. Read more about the genomic catalog of Earth’s microbiomes on the JGI website.
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