Each year, the Berkeley Lab Director’s Achievement Award program recognizes outstanding contributions by employees to all facets of Lab activities. Several Biosciences Area personnel are among the 2022 honorees.
Genentech researchers used a suite of methods, including small-angle X-ray scattering (SAXS) at the Advanced Light Source (ALS) to learn how an assembly of three proteins works together to transmit signals for cell division. The work reveals new targets for the development of drugs that fight certain types of cancer, including lung, colorectal, and pancreatic.
A new paper from Biosciences researchers in the Environmental Genomics and Systems Biology Division, the Molecular Biophysics and Integrated Bioimaging Division, and the Joint BioEnergy Institute (JBEI) reveals the possibility that many of the proteins we thought we knew actually exist in other, unknown shapes.
Researchers at Arizona State University’s Biodesign Institute conducted the first systematic study of Holliday junctions—the nexus of two segments of double-stranded DNA—using crystallography techniques performed at the Advanced Light Source, the Argonne Photon Source, and the National Synchrotron Light Source II.
A recent study published in Nature Plants used a combination of genetic mutation and X-ray crystallography, conducted at the Berkeley Center for Structural Biology, to reveal structural details of a key enzyme involved in plant signaling.