William Jagust

Medical Senior Faculty Scientist, Berkeley Lab
Professor of Public Health and Neuroscience, UC Berkeley

Molecular Biophysics and Integrated Bioimaging

Cellular and Tissue Imaging

Building: 55, Room 219
Mail Stop: 55R0121
Phone: (510) 486-5065
Fax: (510) 486-4768
WJJagust@lbl.gov
http://jagustlab.neuro.berkeley.edu

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Location, Location, Location: Regional Tau Deposits in Healthy Elders Predict Alzheimer Disease

March 4, 2021

Xi Chen and her colleagues in Bill Jagust’s research group at Berkeley Lab recently published a study in the Journal of Neuroscience that provides some clarification of the differences between normal aging and AD brains, and elucidates the transition from the former to the latter.

UCB Study Finds Sleep May Be a Biomarker for Dementia

August 1, 2019

Research led by UC Berkeley scientists found that adults who reported a decline in sleep quality in midlife (40s–60s) had more beta amyloid and tau clusters in their brains—both of which are associated with a higher risk of developing dementia later in life. The same study also revealed that people with high levels of tau protein in their brains were more likely to lack the synchronized brain waves that are crucial to getting a good night’s sleep. Together, the findings suggest that sleep changes detectable in a simple overnight sleep study may serve as biomarkers for later risk of dementia.

Jagust Wins Radical Ideas in Brain Science Challenge

February 22, 2019

Congratulations to William Jagust, senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging Division, for winning the 2018 Radical Ideas in Brain Science Challenge, made possible through the generosity of Berkeley Brain Initiative donors. Jagust, who is also Professor of Public Health at UC Berkeley, will receive up to $190,000 over two years to investigate the degradation of the blood-brain barrier as a potential paradigm-shifting culprit in Alzheimer’s disease and other dementias.

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