Nikos Kyrpides

Computational Biologist Senior Scientist

DOE Joint Genome Institute

Secondary Affiliation: Environmental Genomics and Systems Biology

Biosystems Data Science

Building: 91, Room 439
Mail Stop: 91R183
Phone: (925) 998-0788
NCKyrpides@lbl.gov

Research Interests

Metagenomics, Microbial Genomics, Microbial Diversity, Microbiology, Bioinformatics

Selected Publications

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Taking Stock of the Known and Unknown Microbial Space

January 17, 2025

In Science Advances, JGI researchers have taken stock of the current state of microbial genomic biodiversity. Using publicly available genome sequence data generated over the past three decades, their study assesses what fraction of the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.

The JGI Doubles Down on Known Protein Families

October 16, 2023

Through a novel approach detailed in Nature, a massive computational analysis of microbiome datasets by the JGI focuses on unveiling protein functional diversity.

A Tool to Find Nomadic Genes that Help Microbes Adapt

September 21, 2023

Mobile genetic elements (MGEs) are genetic entities that seek to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool recently described in Nature Biotechnology called geNomad identifies and classifies MGEs based upon their gene content and their genetic sequences. The software was created by researchers under the direction of JGI Microbiome Data Science Group Lead Nikos Kyrpides.

Research Interests

About Biosciences

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