Research Interests

Our lab’s research is focused in four intersecting and complementary areas: mechanisms of ion channel function, synapse development and plasticity, neural circuit function, and the design of novel probes for the optical detection of neuronal signaling.

Developing Tools to Study Neurons
Elucidating structural and functional connectivity between neurons is one of today’s greatest challenges of systems neuroscience. We have developed a family of genetically-encoded photoactivatable calcium sensors that allow us to simultaneously visualize the morphology and activity of individual neurons, including fine structures such as dendritic spines.

Selected Publications

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