Adam M. Deutschbauer

Department Head, Comparative and Functional Genomics
Biologist Staff Scientist

Environmental Genomics and Systems Biology

Comparative and Functional Genomics

Building: 977, Room 261
Phone: (510) 486-5473
AMDeutschbauer@lbl.gov

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Dub-seq Used to Screen Phage Proteins for Antibiotic Properties

March 14, 2023

As conventional antibiotics continue to lose effectiveness against evolving pathogens, scientists are keen to employ the bacteria-killing techniques perfected by bacteriophages (phages), the viruses that infect bacteria. One major challenge is the difficulty of studying individual phage proteins and determining precisely how the virus wields these tools to kill their host bacteria. A team of researchers from Berkeley Lab, UC Berkeley, and Texas A&M University worked together on a high-throughput genetic screen to identify which part of the bacteria the phages were targeting.

Comparative Functional Genomics Department Leadership Change

January 4, 2022

Environmental Genomics and Systems Biology Division Director Susannah Tringe announced a change in leadership of the Comparative and Functional Genomics (CFG) Department, effective January 4, 2022. Diane Dickel is stepping down as the Department Head; Adam Deutschbauer has agreed to take on the role.

New Protein Functions from Beneficial Human Gut Bacterium

March 8, 2021

Researchers in the Environmental Genomics and Systems Biology (EGSB) and Biological Systems and Engineering (BSE) Divisions at Berkeley Lab employed a large-scale functional genomics approach to systematically characterize Bacteroides thetaiotaomicron, a beneficial bacterium prevalent in the human gut. They performed hundreds of genome-wide fitness assays and identified new functions for 40 proteins, including antibiotic tolerance, polysaccharide degradation, and colonization of the GI tract in germ-free mice.

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