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Greater levels of pathological tau protein, primarily in the brain’s medial temporal lobe (orange and yellow at bottom in cross section of the brain), were associated with weaker synchrony of slow waves (red) and sleep spindles (orange), two brain waves important for storing memories while we sleep. (Credit: Matthew Walker and Joseph Winer/UC Berkeley) Susannah Tringe and James Rosenblum at a hydraulic fracking site in Colorado. (Credit: James Rosenblum) The central area of chromosomes, the centromere, contains DNA that has survived largely unchanged for hundreds of thousands of years, researchers at UC Davis and the Lawrence Berkeley Laboratory have found. (Credit: Sasha and Charles Langley) EM image of Pseudomonas phage Pf, an inovirus infecting Pseudomonas hosts. Inovirus capsids are long flexible filaments visible here after sample concentration and precipitation. (Courtesy of J. Driver and P. Secor, University of Montana) The lipid producing yeast, Yarrowia lipolytica, examined with light microscopy (left) and fluorescence microscopy (right), after being stained with Nile Red to visualize the lipid droplets inside (shown here in white). (Courtesy of Hal Alper) Detection of Percc1 expressing cells (red) amongst the epithelial cells (green) of the intestinal villi in a mouse. (Credit: Marco Osterwalder/Berkeley Lab) FISH of Nha-C enrichment with Hrr. lacusprofundi ACAM34-hmgA. Fluorescence micrograph shows individual Nha-C cells amongst Hrr. lacusprofundi cells. Nha-C cells labelled with a Cy5 (red fluorescence) conjugated probe; Hrr. lacusprofundi cells labelled with a Cy3 (yellow fluorescence, recolored to green to improve contrast) probe; all nucleic-acid containing cells stained with DAPI (blue fluorescence). Composite image of all three filters. Scale bars represent 2 µm. (Josh Hamm, UNSW) PECASE winner Wenjun Zhang

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