The Agile BioFoundry and Lygos, Inc. are joining forces to generate the largest multi-omics dataset for guiding the development of organic acids. Over the course of the project, scientists will produce more than 500,000 data points from a series of experiments. ABF is now using its artificial neural networks to train machine learning algorithms and provide actionable recommendations to help optimize strain performance, increase operational efficiencies and enhance production.
Q&A: Molecular Imaging Behind COVID-19 Breakthroughs
A team led by Paul Adams, director of Berkeley Lab’s Molecular Biophysics and Integrated Bioimaging Division, developed the Phenix software suite, now used around the world to automate key steps in the structural biology workflow. Adams spoke with the Strategic Communications about the software’s origins and how structural biologists leapt into action to combat the pandemic.
The Next 90: Biosciences Past, Present, and Future
As part of Berkeley Lab’s 90th Anniversary, we’re reflecting back in history on all that has been accomplished in biological sciences; talking in the present with Associate Laboratory Director for Biosciences, Mary Maxon; and looking forward to the future with project scientist Nathalie Elisabeth in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division.
Mary Maxon Writes About Bioengineering for the Future
Mary Maxon, Associate Lab Director for Biosciences, co-wrote the cover story for the March/April 2021 edition of The Environmental Law Institute’s (ELI) policy magazine, The Environmental Forum. Maxon and her co-author, David Rejeski, a visiting scholar at ELI, discussed everything related to the bioeconomy: economic activity that is driven by research and innovation in the life sciences and biotechnology, and that is enabled by technological advances in engineering and in computing and information sciences.
New Protein Functions from Beneficial Human Gut Bacterium
Researchers in the Environmental Genomics and Systems Biology (EGSB) and Biological Systems and Engineering (BSE) Divisions at Berkeley Lab employed a large-scale functional genomics approach to systematically characterize Bacteroides thetaiotaomicron, a beneficial bacterium prevalent in the human gut. They performed hundreds of genome-wide fitness assays and identified new functions for 40 proteins, including antibiotic tolerance, polysaccharide degradation, and colonization of the GI tract in germ-free mice.
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