Researchers from the Baylor College of Medicine employed previously constructed DNA-encoded chemistry technology (DEC-tec) libraries to identify several candidate molecules that could inhibit the action of Mpro, the main protease of SARS-CoV-2. In a recent study, the researchers described CDD-1713, a new inhibitor to the enzyme Mpro that is involved in propagating the virus. The X-ray crystallographic data, which was collected by Banumathi Sankaran in the Molecular Biophysics and Integrated Bioimaging Division, allowed the researchers to determine that CDD-1713 inhibits the activity of Mpro by binding in the active site of this enzyme.
Breaking Ground on BioEPIC
On October 28, Berkeley Lab marked the groundbreaking for the Biological & Environmental Program Integration Center (BioEPIC), a next-generation facility for studying interactions among microbes, water, soil, and plants. The groundbreaking ceremony at the Bayview site included members of Berkeley Lab leadership, science groups involved with BioEPIC, site cleanup and construction groups, and the construction contractor.
Rachbauer Wins First Place at Bay Area Research SLAM Competition
Lydia Rachbauer, a postdoctoral researcher at the Joint BioEnergy Institute (JBEI) in the Biosciences Area’s Biological Systems and Engineering Division was selected for first place and people’s choice prizes in the inaugural Bay Area Research SLAM competition on October 28. Rachbauer delighted the audience and judges with her three-minute story on utilizing the microbes found in fish guts to convert seaweed into sustainable biofuels.
Integrative Genomics Building Receives DOE Project Management Achievement Award
On October 25, 2021, the Department of Energy recognized the completion of the Integrative Genomics Building (IGB) with a 2020 Project Management Achievement Award. According to the IGB project management award citation, project managers oversaw the completion of the building ahead of schedule and on budget in a highly competitive construction environment.
Biosciences Area in Basics2Breakthroughs
Three Biosciences Area members were recently highlighted in the video series, Basics2Breakthroughs, which focuses on early career scientists discussing their research and what they hope for the future in that research.
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