Stanford researchers have used cryogenic 3D imaging at the National Center for X-ray Tomography (NCXT) to identify a new pathway for clearing misfolded proteins from cells. This work presents a potential therapy target for age-related disorders like Alzheimer, Parkinson, and Huntington Diseases.
Bacteria Can Make Infinitely Recyclable Plastic with Renewable Materials
A collaboration among experts at the Molecular Foundry, the Joint BioEnergy Institute (JBEI), and the Advanced Light Source has shown that the starting ingredients in an infinitely recyclable plastic known as poly(diketoenamine), or PDK, can be successfully made by microbes. The new approach shows that renewable, recyclable plastics are not only possible, but also outperform those from petrochemicals.
JGI Researchers Trace Strawberry Ancestors For a View of Crop Evolution
In the summer of 2015, Adam Session was a postdoc working at the DOE Joint Genome Institute with Dan Rokhsar, who also holds a joint appointment with the University of California, Berkeley. Nowadays, Session is an Assistant Professor at Binghamton University in New York. He and Rokhsar have recently published a Nature Communications paper that builds off their early collaborations that could help crop breeders and researchers predict how crops and model organisms may evolve.
Breaking Barriers in Drug Delivery with Better Lipid Nanoparticles
Berkeley Lab and Genentech are collaborating to make the next generation of lipid nanoparticles (LNPs), the drug delivery technology used in the COVID-19 vaccines. With their combined expertise in structural biology and pharmaceutical science, the team is designing LNPs that can precisely deliver vaccines and therapeutics to target tissues while improving the product’s shelf life and duration of action.
A Roadmap for Gene Regulation in Plants
A team of researchers from the Joint BioEnergy Institute’s (JBEI) Feedstocks Division has, for the first time, developed a genome-scale way to map the regulatory role of transcription factors, the proteins that play a key role in gene expression and determining a plant’s physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize genetic engineering efforts in plants.
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