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A laser (purple) is powerfully amplified by highly polished mirrors and focused on the electron beam (blue) to shift its phase and increase the cryo-EM microscope’s contrast, allowing biologists to image smaller proteins and the crowded structures inside cells. (Credit: Credit: SayoStudio/Biohub) Two flasks with light brown and dark red liquids, held by a blue glove. Indigo mushrooms against a background of grass A blue protein structure diagram showing open and closed lids, and a complex structure with labeled terms. Photo of recipient next to NAS logo. The image shows mature sorghum panicles shaped against a sunrise sky.

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