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Breaking the Xylose Bottleneck
Xylose utilization remains the primary bottleneck in fully using the renewable plant biomass. In a Nature Scientific Reports paper entitled, “Evolved hexose transporter enhances xylose uptake and glucose/xylose co-utilization in Saccharomyces cerevisiae,” Biological Systems & Engineering Division researchers at Joint BioEnergy Institute (JBEI) Amanda Reider Apel and Aindrila Mukhopadhyay report the discovery and characterization of a yeast sugar transporter variant with superior Vmax (uptake rates) for xylose. This discovery will be valuable in developing biomanufacturing strains that can use the full set of sugars generated from plant biomass. Read more on the JBEI website.
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Scientists Discover Protein’s Starring Role in Genome Stability, and Possibly Cancer Prevention
If you have a soft spot for unsung heroes, you’ll love a DNA repair protein called XPG. Berkeley Lab scientists discovered that XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. Their findings also raise the possibility that the protein helps prevent breast, ovarian, and other cancers associated with defective BRCA genes. The work, which is published online January 28 in the journal Molecular Cell, indicates XPG is essential to our health in ways far beyond it’s been given credit for. Priscilla Cooper of the Biological Systems and Engineering Division conducted the research…
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The Secretary of Energy Advisory Board (SEAB) held a public session at Emery Station
The Secretary of Energy Advisory Board (SEAB) held a public session on Tuesday, January 26 at the Biosciences Area’s Emery Station Operations Center (ESOC). Berkeley Lab’s Director Paul Alivisatos gave a Lab overview. Jennifer Doudna was invited by SEAB to give a briefing of CRISPR-Cas and Ilan Gur led a roundtable discussion on the activities of […]
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Simmons Named Division Director for Biological Systems and Engineering
Jay Keasling, Associate Laboratory Director for Biosciences, announced that Blake Simmons has accepted the position of Division Director for Biological Systems and Engineering (BSE) effective February 10, 2016. He will retain his positions as Chief Scientific and Technology Officer and as the Vice President of the Deconstruction Division at the Joint BioEnergy Institute.
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JBEI Appoints New VP and Deputy VP of Fuels Synthesis Division
The Department of Energy’s Joint Bioenergy Institute (JBEI) Chief Executive Officer, Jay Keasling, has announced that Aindrila Mukhopadhyay will step into the role of Vice President of the Fuels Synthesis Division. This announcement comes after a national search and interview process. Mukhopadhyay, who joined the Lawrence Berkeley National Laboratory (Berkeley Lab) in 2003, will continue to serve as Director of JBEI’s Host Engineering group and as Interim Division Director of Berkeley Lab’s Biological Systems and Engineering (BSE) in the Biosciences Area.
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