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Three from Biosciences Area Named AAAS Fellows
The American Association for the Advancement of Science (AAAS), which was founded in 1848 and is the world’s largest general scientific society, announced that 489 of its members—among them nine scientists at Berkeley Lab—have been named Fellows. This lifetime honor, which follows a nomination and review process, recognizes scientists, engineers, and innovators for their distinguished achievements toward the advancement or applications of science. The three newly named Fellows from the Biosciences Area are: Sanjay Kumar, a faculty scientist in the Biological Systems and Engineering (BSE) Division; Mary Maxon, the Associate Laboratory Director for the Biosciences Area; and Len Pennacchio, a…
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Mina Bissell Delivers Gairdner Laureate Talk Virtually, Receives Medal at Home
This spring, Mina Bissell, distinguished senior scientist in the Biological Systems and Engineering (BSE) Division, was awarded the 2020 Canada Gairdner International Award for Biomedical Research. Due to the ongoing coronavirus pandemic, the Gairdner Foundation held their annual Laureate Lectures and Gala Celebration—normally hosted in Toronto, Ontario, Canada—virtually this year. Bissell presented her talk, entitled “Why Don’t We Get More Cancer?”, about a signaling pathway she and her research group discovered that doesn’t get turned off in cancer and leads to uncontrolled growth. She received her medal surrounded by family at home in Berkeley, and spoke about the power of…
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Machine Learning Takes on Synthetic Biology: Algorithms Can Bioengineer Cells for You
Engineering biological systems to specification–for example, designing a microbe to produce a cancer-fighting agent–requires a detailed mechanistic understanding of how all the parts of a cell work. Typically, this knowledge is acquired through years of painstaking work and a fair amount of trial and error. But Berkeley Lab scientists have created an Automated Recommendation Tool (ART) that adapts machine learning algorithms to the needs of synthetic biology to guide development systematically. With a limited set of training data, the algorithms are able to predict how changes in a cell’s DNA or biochemistry will affect its behavior, then make recommendations for…
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Videos Showcase Biosciences’ Response to COVID-19
For the past several months, teams of bioscientists have utilized Berkeley Lab’s world-class research facilities to contribute to the national response to COVID-19, resulting in a wide range of promising research. Four videos showcase researcher contributions from across the Biosciences Area, which aim to help address some of the many scientific challenges posed by the pandemic.
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Finding the Missing Step of an Important Molecular Process
Lysine is an important amino acid that must be supplied in our diets, as our bodies can’t produce lysine on their own. Most cereal grains have low levels of lysine, and scientists have worked to breed crops with higher lysine levels. However, the biochemical processes that break down lysine in plants weren’t fully understood. New Joint BioEnergy Institute (JBEI) research, published in Nature Communications, reveals this last missing step of lysine catabolism.
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