Collage capturing a diverse set of bacteria and functions that can be better understood using DAP-seq. (Eduardo de Ugarte, Berkeley Lab)

One of the tools that researchers can apply to study the transcription factors that control how genes are turned on is known as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan O’Malley, who leads the JGI Sequencing Technologies Group. In a Nature Methods article, JGI researchers led by co-first authors Leo Baumgart and Juna Lee developed two approaches that build upon the DAP-seq technology O’Malley developed.  Read more here on the JGI website.