James Holton, a faculty scientist in the Molecular Biophysics and Bioimaging (MBIB) Division and full adjunct professor of biochemistry and biophysics at the University of California, San Francisco (UCSF), is the 2020 recipient of the American Crystallographic Association’s David J. Rognlie Award. Bestowed every third year, the prize recognizes “an exceptional discovery or technical development of particularly high impact in any area of structural science.” Holton is being honored for his work in the development of the beamline 8.3.1 at the Advanced Light Source (ALS) at Berkeley Lab, one of the most productive beamlines in the world. The citation notes that he has made numerous pioneering contributions to the synchrotron experience, starting with a vision for optimizing all aspects of data collection to structure determination and developing and implementing novel hardware and software solutions. Holton’s software developments allow users to solve problems concurrent with data collection, rather than after leaving the beamline. The award will be presented during the 2020 ACA Annual Meeting, to be held virtually August 2–7.