Working at temperatures near absolute zero, scientists at Berkeley Lab and UC Berkeley have captured images of proteins at work in the early steps of DNA transcription. Eva Nogales, a senior faculty scientist at in the Molecular Biophysics & Integrated Bioimaging Division, UC Berkeley professor of biochemistry and a Howard Hughes Medical Institute (HHMI) investigator, led the new study, published today in the journal Nature.

This latest research comes seven weeks after Nogales unveiled an earlier milestone using cryo-EM technology to image details of transcription factor TFIID in gene expression. Read the full UC Berkeley press release on the newest Nature paper.