The projects of 22 Biosciences Area scientists and engineers received funding through the FY23 Laboratory Directed Research and Development (LDRD) program.
Biosciences Area in Basics2Breakthroughs
Three Biosciences Area members were recently highlighted in the video series, Basics2Breakthroughs, which focuses on early career scientists discussing their research and what they hope for the future in that research.
Biosciences Area FY22 LDRD Projects
The projects of 17 Biosciences Area scientists and engineers received funding through the FY22 Laboratory Directed Research and Development (LDRD) program.
Microbe “Rewiring” Technique Promises a Boom in Biomanufacturing
A new approach to modifying microbes’ metabolic processes will speed up production of innovative bio-based fuels, materials, and chemicals
Researchers from Lawrence Berkeley National Laboratory (Berkeley Lab) have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing.
JBEI Researchers Improve Membrane Protein Expression And Function Using Genomic Edits
Development of robust microbial platforms for bioproduction requires strains that have been engineered to have efficient carbon uptake, energy generation, tolerance to biomass pretreatment byproducts and the export of final product. Many of these optimizations require expression and overexpression of native and heterologous membrane proteins. Over the years, scientists at the U.S. Department of Energy’s Joint BioEnergy Institute (JBEI), and others have successfully found many such engineering targets. However, JBEI has also found that expression of membrane proteins is challenging and can also impact the microbial growth, thus negatively limiting the use of these discoveries. Read more from JBEI.
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