During the annual Lorne Conference on Protein Structure and Function in Australia last month, Ian van Driel of the University of Melbourne (left) presented MBIB senior faculty scientist Eva Nogales (center) with the Grimwade Medal for Biochemistry for “visualizing the molecular dance at the heart of human gene expression.” The award is funded by the Grimwade family, pioneers in Australia’s pharmaceutical industry, of which Sir Andrew Grimwade (right) is a member. While in Australia, Nogales was a guest on the University of Melbourne’s “Eavesdrop on Experts” podcast. She spoke with host Steve Grimwade about using cryo-EM to understand cell behavior at the molecular level.
Learn More About Cyclotron Road Fellows With ‘Backstories’ Series
Jill Fuss, research scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, and Steve Yannone, former MBIB scientist, are creating the future of clean energy, advanced manufacturing, and electronics. Both are currently participating in Cyclotron Road, which is using the “Backstories” series to shine a light on the journeys researchers have taken to develop their technologies through videos and storytelling.
Nanotubes Simplify Genetic Engineering of Plants
Molecular Biophysics and Integrated Bioimaging (MBIB) faculty scientist Markita Landry has developed a simplified technique for genetically engineering any type of plant that could speed the introduction of new and beneficial genes. While trying to label plant cells with nanotube sensors, Landry, an assistant professor in UC Berkeley’s chemical and biomolecular engineering department, discovered that nanotubes easily slip though plant cell walls, which are known for their tough layers. She immediately saw how to flip this around to deliver genes into plants; she and her colleagues describe the technique in Nature Nanotechnology.
Jagust Wins Radical Ideas in Brain Science Challenge
Congratulations to William Jagust, senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging Division, for winning the 2018 Radical Ideas in Brain Science Challenge, made possible through the generosity of Berkeley Brain Initiative donors. Jagust, who is also Professor of Public Health at UC Berkeley, will receive up to $190,000 over two years to investigate the degradation of the blood-brain barrier as a potential paradigm-shifting culprit in Alzheimer’s disease and other dementias.
Two New Additions to CRISPR Toolkit
UC Berkeley and Berkeley Lab scientists have expanded the CRISPR gene-editing toolkit with the addition of a new, compact CRISPR-associated (Cas) protein—the RNA-guided “scissors” that snip DNA—and a modification of the Cas9 protein to give it an “on” switch for better control.
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