Nicholas Sauter, a computer senior scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, is co-leading a team working to provide a better way for scientists to study the structures of the many materials that don’t form tidy single crystals. Their new technique, called small-molecule serial femtosecond X-ray crystallography, or smSFX, supercharges traditional crystallography with the addition of custom-built image processing algorithms and an X-ray free electron laser (XFEL). In a paper published in Nature, the team demonstrated proof-of-principle for smSFX and reported the previously unknown structures of two metal-organic materials known as chacogenolates.
Congratulations to 2021 Chan Zuckerberg Biohub Investigators
The Chan Zuckerberg Biohub Investigator Program recently awarded $21 million to 21 University of California, Berkeley researchers. Of this group, four are faculty scientists in the Biosciences Area.
All-star Scientific Team Seeks to Edit Entire Microbiomes with CRISPR
CRISPR enzymes are like super scissors: they cut, delete, and add genes to a specific kind of cell, one at a time. But now, UC Berkeley faculty and Biosciences Area researchers have figured out how to add or modify genes within a microbial community of many different species, coining the phrase, “community editing.”
New Device Advances Commercial Viability of Solar Fuels
A research team led by Francesca Toma, a staff scientist in the Liquid Sunlight Alliance (LiSA) and Chemical Sciences Division (CSD), has developed an artificial photosynthesis device with remarkable stability and longevity as it converts sunlight and carbon dioxide into ethylene and hydrogen—two promising sources of renewable fuels. The team used electron microscopy at the Molecular Foundry and ambient pressure X-ray photoelectron spectroscopy (APXPS) at the Advanced Light Source to reveal how the device degrades with use, then demonstrate how to mitigate those processes.
Chloro-phylling in the Answers to Big Questions
A team of scientists, including many in the Molecular Biophysics and Integrated Bioimaging Division, uncovered new details about the reaction that powers photosynthesis. Understanding this reaction could lead to world-changing advances in technology, medicine, or energy––and also gives insight into how the enzyme photosystem II produces the oxygen we breathe. Their latest work was recently published in Nature Communications and two of the authors, Vittal Yachandra and Philipp Simon, spoke with Strategic Communications about that, shooting stuff with lasers, and why they chose this field of research.
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