In Nature, a team led by researchers at the University of Texas at Austin, the HudsonAlpha Institute for Biotechnology, and DOE Joint Genome Institute has produced a high-quality reference sequence of the complex switchgrass genome. Building off this work, researchers at all four DOE Bioenergy Research Centers—the Great Lakes Bioenergy Research Center, the Center for … Read more »
Susannah Tringe Honored with the Lawrence Award
The Department of Energy has announced that eight distinguished scientists and engineers will receive the Ernest Orlando Lawrence Award, one of DOE’s highest honors. Named after Berkeley Lab’s founder, the award was established in 1959 and recognizes mid-career researchers for exceptional contributions supporting the DOE and its mission to advance the national, economic, and energy security of the United States.
JGI’s CheckV Tool to Assess Virus Data Quality
Assembling viral genomes from metagenomes is challenging and often results in highly fragmented data, which limits the ability of researchers to accurately perform functional assessment, host prediction, and phylogenetic analysis. As reported in Nature Biotechnology, a team including JGI’s Stephen Nayfach, Frederik Schulz, Emiley Eloe-Fadrosh, Simon Roux and Nikos Kyrpides developed an automated tool called CheckV (pronounced “Check-Vee”) to help researchers assess and improve the quality of metagenome-assembled viral genomes. CheckV has already been applied to over 2.4 million viral genomes available in the latest release of IMG/VR, a database that is part of the Integrated Microbial Genomes & Microbiomes (IMG/M) suite. Learn more here on the JGI website.
JGI Launches Data Portal for Algae
A JGI team led by Algal Genomics Program lead Igor Grigoriev and data scientist Alan Kuo have unveiled PhycoCosm in the Nucleic Acids Research journal. The genome portal reinforces the JGI’s new strategic focus on exploring algal biology, diversity, and ecology. Read more here on the JGI website.
JGI Helps Unlock How Maize Makes An Antibiotic Cocktail
Maize (Zea mays) produces a plethora of antibiotics called zealexins. These compounds protect maize by fending off fungal and microbial infections. Scientists had assumed that maize synthesizes these compounds via clear, straight pathways, entailing the function of more than a dozen enzymes. But now, with the help of JGI’s DNA synthesis capability, researchers know that just a handful of enzymes are needed to transform zealexins and related precursors into a bonanza of diverse structures. Read more of the science highlight on the JGI website.
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