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New Microscopy Technique Gives Detailed 3D View Inside Cells

January 23, 2020

A new microscopy technique combines electron microscopy and light microscopy to generate detailed, three-dimensional images of cells. Credit: D. Hoffman et al./Science 2020

A team led by Harald Hess at the Howard Hughes Medical Institute (HHMI) Janelia Research Campus and Eric Betzig, a senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division, has devised a technique that combines cryogenic super-resolution fluorescence microscopy and focused ion beam–milling scanning electron microscopy. In a report in the journal Science, the researchers describe their technique, called cryo-SR/EM, and display some of exquisitely detailed three-dimensional images they captured of the complex innards of cells.

Nobel Prize Winner, World-Class Biophysicist to Join Biosciences

October 4, 2016

Chemistry Nobelist Eric Betzig and world-class biophysicist Na Ji will join Berkeley Lab and UC Berkeley in the summer of 2017. They will serve as faculty scientists in the Molecular Biophysics & Integrated Bioimaging Division of the Biosciences Area.

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