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Comparative Functional Genomics Department Leadership Change

January 4, 2022

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Environmental Genomics and Systems Biology Division Director Susannah Tringe announced a change in leadership of the Comparative and Functional Genomics (CFG) Department, effective January 4, 2022. Diane Dickel is stepping down as the Department Head; Adam Deutschbauer has agreed to take on the role.

Report from Second Plant Single-cell Solutions for Energy and the Environment Workshop Available

December 20, 2021

On April 29, 2021, Berkeley Lab hosted a second workshop to identify the most pressing barriers to wider adoption of single-cell sequencing and omics technologies, and to discuss solutions to remedy those barriers in order to drive discovery. The workshop report is now available for download.

Women @ the Lab Awards

March 31, 2021

Four Biosciences employees were selected by Berkeley Lab leadership and the Women Scientists and Engineers Council (WSEC) for recognition as part of the 2020 Women @ the Lab awards. The biennial program, now in its fourth year, spotlights women at the Lab for meritorious professional contributions, leadership, mentorship, and outreach.

The Paradox of ‘Ultraconserved’ Enhancers: Perfect Sequence Conservation Not Required

March 30, 2021

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The last common ancestor of humans and rodents lived more than 80 million years ago, and billions of changes in their respective DNA sequences have occurred over this vast timespan. Yet, intriguingly, there are a few hundred stretches of DNA in our genome that are still identical to the corresponding sequences in mice and rats. Generally, sequence conservation between distantly related species is an indication that the function the DNA serves is vitally important and highly sensitive to mutations. For example, most DNA sequences that encode proteins show at least moderate conservation in evolution. However, more than two-thirds of the “ultraconserved” sequences shared by humans and rodents are outside of protein-coding genes, raising the question of what led to their extreme level of conservation.

Plant Single-cell Solutions for Energy and the Environment Workshop Report Released

October 7, 2020

On January 23, 2020, Berkeley Lab hosted a workshop on opportunities afforded by single-cell technologies for energy and environmental science, as well as conceptual and technological grand challenges that must be tackled to apply these powerful approaches to plants, fungi and algae. This event, which was spearheaded by Diane Dickel in the Environmental Genomics and Systems Biology Division, brought together a diverse group of leaders in functional genomics technologies from academia, the National Laboratories, and local research institutions.

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